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Detecting Rare Variants in Case-Parents Association Studies

Despite the success of genome-wide association studies (GWASs) in detecting common variants (minor allele frequency ≥0.05) many suggested that rare variants also contribute to the genetic architecture of diseases. Recently, researchers demonstrated that rare variants can show a strong stratification...

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Detalhes bibliográficos
Main Authors: Cheng, Kuang-Fu, Chen, Jin-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784439/
https://ncbi.nlm.nih.gov/pubmed/24086332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074310
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