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Insulin responsiveness of glucose transporter 4 in 3T3-L1 cells depends on the presence of sortilin
Insulin-dependent translocation of glucose transporter 4 (Glut4) to the plasma membrane of fat and skeletal muscle cells plays the key role in postprandial clearance of blood glucose. Glut4 represents the major cell-specific component of the insulin-responsive vesicles (IRVs). It is not clear, howev...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Cell Biology
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3784384/ https://ncbi.nlm.nih.gov/pubmed/23966466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-10-0765 |
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