Whole blood stimulation with Toll-like receptor (TLR)-7/8 and TLR-9 agonists induces interleukin-12p40 expression in plasmacytoid dendritic cells in rhesus macaques but not in humans

Macaques provide important animal models in biomedical research into infectious and chronic inflammatory disease. Therefore, a proper understanding of the similarities and differences in immune function between macaques and humans is needed for adequate interpretation of the data and translation to...

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Bibliographic Details
Main Authors: Koopman, G, Beenhakker, N, Burm, S, Bouwhuis, O, Bajramovic, J, Sommandas, V, Mudde, G, Mooij, P, 't Hart, B A, Bogers, W M J M
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2013
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784223/
https://ncbi.nlm.nih.gov/pubmed/23750720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12155
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