The PLK1 Inhibitor GSK461364A Is Effective in Poorly Differentiated and Anaplastic Thyroid Carcinoma Cells, Independent of the Nature of Their Driver Mutations

BACKGROUND: Poorly differentiated thyroid carcinoma (PDTC) and anaplastic thyroid carcinoma (ATC) are the most aggressive forms of thyroid cancer. Despite their low incidence, they account for a disproportionate number of thyroid cancer–related deaths because of their resistance to most therapeutic...

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Bibliografiset tiedot
Päätekijät: Russo, Marika A., Kang, Kristy S., Di Cristofano, Antonio
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Mary Ann Liebert, Inc. 2013
Aiheet:
Thyroid Cancer and Nodules
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783934/
https://ncbi.nlm.nih.gov/pubmed/23509868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2013.0037
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