Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors

Anaplastic thyroid carcinoma (ATC) is the most aggressive form of thyroid cancer, and often derives from pre-existing well-differentiated tumors. Despite a relatively low prevalence, it accounts for a disproportionate number of thyroid cancer-related deaths, due to its resistance to any therapeutic...

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Hauptverfasser: Arciuch, Valeria G. Antico, Russo, Marika A., Dima, Mariavittoria, Kang, Kristy S., Dasrath, Florence, Liao, Xiao-Hui, Refetoff, Samuel, Montagna, Cristina, Di Cristofano, Antonio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2011
Schlagworte:
Research Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282070/
https://ncbi.nlm.nih.gov/pubmed/22190384
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