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The Metal-Drug Synergy: New Ruthenium(II) Complexes of Ketoconazole are Highly Active against Leishmania major and Trypanosoma cruzi and Non-toxic to Human or Murine Normal Cells
In our ongoing search for new metal-based chemotherapeutic agents against leishmaniasis and Chagas disease, six new ruthenium-ketoconazole (Ru-KTZ) complexes have been synthesized and characterized, including two octahedral coordination complexes cis-fac-[Ru(II)Cl(2)(DMSO)(3)(KTZ)] (1) and cis-[Ru(I...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3783607/ https://ncbi.nlm.nih.gov/pubmed/23881220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-013-1024-2 |
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