Calpastatin prevents NF-κB mediated hyperactivation of macrophages and attenuates colitis

Calpain enzymes proteolytically modulate cellular function and have been implicated in inflammatory diseases. In this study, we found that calpain levels did not differ between intestinal tissues from inflammatory bowel disease (IBD) patients and healthy controls, but IBD tissues showed increased le...

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Библиографические подробности
Главные авторы: Huang, Zhi, Rose, Aaron H., Hoffmann, FuKun W., Hashimoto, Ann S., Bertino, Pietro, Denk, Tobias, Takano, Jiro, Iwata, Nobuhisa, Saido, Takaomi C., Hoffmann, Peter R.
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783572/
https://ncbi.nlm.nih.gov/pubmed/23986533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300972
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