Deciphering the modulation of gene expression by type I and II interferons combining 4sU-tagging, translational arrest and in silico promoter analysis

Interferons (IFN) play a pivotal role in innate immunity, orchestrating a cell-intrinsic anti-pathogenic state and stimulating adaptive immune responses. The complex interplay between the primary response to IFNs and its modulation by positive and negative feedback loops is incompletely understood....

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Detalhes bibliográficos
Main Authors: Trilling, Mirko, Bellora, Nicolás, Rutkowski, Andrzej J., de Graaf, Miranda, Dickinson, Paul, Robertson, Kevin, Prazeres da Costa, Olivia, Ghazal, Peter, Friedel, Caroline C., Albà, M. Mar, Dölken, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Gene Regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783172/
https://ncbi.nlm.nih.gov/pubmed/23832230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt589
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