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Deciphering the modulation of gene expression by type I and II interferons combining 4sU-tagging, translational arrest and in silico promoter analysis
Interferons (IFN) play a pivotal role in innate immunity, orchestrating a cell-intrinsic anti-pathogenic state and stimulating adaptive immune responses. The complex interplay between the primary response to IFNs and its modulation by positive and negative feedback loops is incompletely understood....
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Главные авторы: | , , , , , , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
Oxford University Press
2013
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3783172/ https://ncbi.nlm.nih.gov/pubmed/23832230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt589 |
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