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Deciphering of the Human Interferon-Regulated Proteome by Mass Spectrometry-Based Quantitative Analysis Reveals Extent and Dynamics of Protein Induction and Repression

Interferons (IFNs) are pleotropic cytokines secreted upon encounter of pathogens and tumors. Applying their antipathogenic, antiproliferative, and immune stimulatory capacities, recombinant IFNs are frequently prescribed as drugs to treat different diseases. IFNs act by changing the gene expression...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Megger, Dominik A., Philipp, Jos, Le-Trilling, Vu Thuy Khanh, Sitek, Barbara, Trilling, Mirko
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603615/
https://ncbi.nlm.nih.gov/pubmed/28959263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01139
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