The Canonical Immediate Early 3 Gene Product pIE611 of Mouse Cytomegalovirus Is Dispensable for Viral Replication but Mediates Transcriptional and Posttranscriptional Regulation of Viral Gene Products

Transcription of mouse cytomegalovirus (MCMV) immediate early ie1 and ie3 is controlled by the major immediate early promoter/enhancer (MIEP) and requires differential splicing. Based on complete loss of genome replication of an MCMV mutant carrying a deletion of the ie3-specific exon 5, the multifu...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Rattay, Stephanie, Trilling, Mirko, Megger, Dominik A., Sitek, Barbara, Meyer, Helmut E., Hengel, Hartmut, Le-Trilling, Vu Thuy Khanh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524224/
https://ncbi.nlm.nih.gov/pubmed/26063418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01234-15
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