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The Canonical Immediate Early 3 Gene Product pIE611 of Mouse Cytomegalovirus Is Dispensable for Viral Replication but Mediates Transcriptional and Posttranscriptional Regulation of Viral Gene Products

Transcription of mouse cytomegalovirus (MCMV) immediate early ie1 and ie3 is controlled by the major immediate early promoter/enhancer (MIEP) and requires differential splicing. Based on complete loss of genome replication of an MCMV mutant carrying a deletion of the ie3-specific exon 5, the multifu...

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Pubblicato in:J Virol
Autori principali: Rattay, Stephanie, Trilling, Mirko, Megger, Dominik A., Sitek, Barbara, Meyer, Helmut E., Hengel, Hartmut, Le-Trilling, Vu Thuy Khanh
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524224/
https://ncbi.nlm.nih.gov/pubmed/26063418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01234-15
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