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Dissecting cancer heterogeneity with a probabilistic genotype-phenotype model

One of the obstacles hindering a better understanding of cancer is its heterogeneity. However, computational approaches to model cancer heterogeneity have lagged behind. To bridge this gap, we have developed a new probabilistic approach that models individual cancer cases as mixtures of subtypes. Ou...

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Detalhes bibliográficos
Main Authors: Cho, Dong-Yeon, Przytycka, Teresa M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783162/
https://ncbi.nlm.nih.gov/pubmed/23821670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt577
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