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Understanding Genotype-Phenotype Effects in Cancer via Network Approaches

Cancer is now increasingly studied from the perspective of dysregulated pathways, rather than as a disease resulting from mutations of individual genes. A pathway-centric view acknowledges the heterogeneity between genomic profiles from different cancer patients while assuming that the mutated genes...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Kim, Yoo-Ah, Cho, Dong-Yeon, Przytycka, Teresa M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786343/
https://ncbi.nlm.nih.gov/pubmed/26963104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004747
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