Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF

Tissue-resident macrophages can develop from circulating adult monocytes or from primitive yolk sac–derived macrophages. The precise ontogeny of alveolar macrophages (AMFs) is unknown. By performing BrdU labeling and parabiosis experiments in adult mice, we found that circulating monocytes contribut...

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Main Authors: Guilliams, Martin, De Kleer, Ismé, Henri, Sandrine, Post, Sijranke, Vanhoutte, Leen, De Prijck, Sofie, Deswarte, Kim, Malissen, Bernard, Hammad, Hamida, Lambrecht, Bart N.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782041/
https://ncbi.nlm.nih.gov/pubmed/24043763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131199
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