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Mismatch Repair Inhibits Homeologous Recombination by Coordinated Directional Unwinding of Trapped DNA Structures
Homeologous recombination between divergent DNA sequences is inhibited by DNA mismatch repair. In Escherichia coli, MutS and MutL respond to DNA mismatches within recombination intermediates and prevent strand exchange by an unknown mechanism. Here, using purified proteins and DNA substrates, we fin...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3781583/ https://ncbi.nlm.nih.gov/pubmed/23932715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.07.008 |
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