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Low-Dose Methotrexate Results in the Selective Accumulation of Aminoimidazole Carboxamide Ribotide in an Erythroblastoid Cell Line

Therapeutic and toxic response to low-dose methotrexate (MTX) in the treatment of autoimmune disease continues to be highly variable, resulting in a critical need to identify predictive biomarkers of response. Biomarker development has been hampered by an incomplete understanding of the molecular ph...

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Bibliografiset tiedot
Päätekijät: Funk, Ryan S., van Haandel, Leon, Becker, Mara L., Leeder, J. Steven
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Pharmacology and Experimental Therapeutics 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781408/
https://ncbi.nlm.nih.gov/pubmed/23887097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.206672
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