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C-C chemokine receptor-7 mediated endocytosis of antibody cargoes into intact cells
The C–C chemokine receptor-7 (CCR7) is a G protein coupled receptor that has a role in leukocyte homing, but that is also expressed in aggressive tumor cells. Preclinical research supports that CCR7 is a valid target in oncology. In view of the increasing availability of therapeutic monoclonal antib...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3781320/ https://ncbi.nlm.nih.gov/pubmed/24068998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2013.00122 |
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