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CpG dinucleotide-specific hypermethylation of the TNS3 gene promoter in human renal cell carcinoma

Tensin3 is a cytoskeletal regulatory protein that inhibits cell motility. Downregulation of the gene encoding Tensin3 (TNS3) in human renal cell carcinoma (RCC) may contribute to cancer cell metastatic behavior. We speculated that epigenetic mechanisms, e.g., gene promoter hypermethylation, might ac...

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Detalhes bibliográficos
Main Authors: Carter, Jessica A., Górecki, Dariusz C., Mein, Charles A., Ljungberg, Börje, Hafizi, Sassan
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781193/
https://ncbi.nlm.nih.gov/pubmed/23803643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.25075
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