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CpG dinucleotide-specific hypermethylation of the TNS3 gene promoter in human renal cell carcinoma

Tensin3 is a cytoskeletal regulatory protein that inhibits cell motility. Downregulation of the gene encoding Tensin3 (TNS3) in human renal cell carcinoma (RCC) may contribute to cancer cell metastatic behavior. We speculated that epigenetic mechanisms, e.g., gene promoter hypermethylation, might ac...

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Autores principales: Carter, Jessica A., Górecki, Dariusz C., Mein, Charles A., Ljungberg, Börje, Hafizi, Sassan
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781193/
https://ncbi.nlm.nih.gov/pubmed/23803643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.25075
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