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Mammalian DNA demethylation: Multiple faces and upstream regulation

DNA cytosine methylation is a reversible epigenetic mark regulating gene expression. Aberrant methylation profiles are concomitant with developmental defects and cancer. Numerous studies in the past decade have identified enzymes and pathways responsible for active DNA demethylation both on a genome...

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Detalhes bibliográficos
Autor principal: Schomacher, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781186/
https://ncbi.nlm.nih.gov/pubmed/23803967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.24977
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