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Mammalian DNA demethylation: Multiple faces and upstream regulation

DNA cytosine methylation is a reversible epigenetic mark regulating gene expression. Aberrant methylation profiles are concomitant with developmental defects and cancer. Numerous studies in the past decade have identified enzymes and pathways responsible for active DNA demethylation both on a genome...

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Hlavní autor: Schomacher, Lars
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781186/
https://ncbi.nlm.nih.gov/pubmed/23803967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.24977
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