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Drug-Induced Reactivation of Apoptosis Abrogates HIV-1 Infection

HIV-1 blocks apoptosis, programmed cell death, an innate defense of cells against viral invasion. However, apoptosis can be selectively reactivated in HIV-infected cells by chemical agents that interfere with HIV-1 gene expression. We studied two globally used medicines, the topical antifungal ciclo...

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Bibliografiska uppgifter
Huvudupphovsmän: Hanauske-Abel, Hartmut M., Saxena, Deepti, Palumbo, Paul E., Hanauske, Axel-Rainer, Luchessi, Augusto D., Cambiaghi, Tavane D., Hoque, Mainul, Spino, Michael, Gandolfi, Darlene D'Alliessi, Heller, Debra S., Singh, Sukhwinder, Park, Myung Hee, Cracchiolo, Bernadette M., Tricta, Fernando, Connelly, John, Popowicz, Anthony M., Cone, Richard A., Holland, Bart, Pe’ery, Tsafi, Mathews, Michael B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781084/
https://ncbi.nlm.nih.gov/pubmed/24086341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074414
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