Drug-Induced Reactivation of Apoptosis Abrogates HIV-1 Infection

HIV-1 blocks apoptosis, programmed cell death, an innate defense of cells against viral invasion. However, apoptosis can be selectively reactivated in HIV-infected cells by chemical agents that interfere with HIV-1 gene expression. We studied two globally used medicines, the topical antifungal ciclo...

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Detalhes bibliográficos
Main Authors: Hanauske-Abel, Hartmut M., Saxena, Deepti, Palumbo, Paul E., Hanauske, Axel-Rainer, Luchessi, Augusto D., Cambiaghi, Tavane D., Hoque, Mainul, Spino, Michael, Gandolfi, Darlene D'Alliessi, Heller, Debra S., Singh, Sukhwinder, Park, Myung Hee, Cracchiolo, Bernadette M., Tricta, Fernando, Connelly, John, Popowicz, Anthony M., Cone, Richard A., Holland, Bart, Pe’ery, Tsafi, Mathews, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781084/
https://ncbi.nlm.nih.gov/pubmed/24086341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074414
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