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Induction of p53, p21 and apoptosis by silencing the NF90/NF45 complex in human papilloma virus-transformed cervical carcinoma cells

The heterodimeric nuclear factor 90/nuclear factor 45 complex (NF90/NF45) binds nucleic acids and is a multifunctional regulator of gene expression. Here we report that depletion of NF90/NF45 restores the expression of the p53 and p21 proteins in cervical carcinoma cells infected with high-risk huma...

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Detalhes bibliográficos
Main Authors: Shamanna, Raghavendra A., Hoque, Mainul, Pe'ery, Tsafi, Mathews, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032571/
https://ncbi.nlm.nih.gov/pubmed/23208500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.533
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