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The Growth Factor Granulin Interacts with Cyclin T1 and Modulates P-TEFb-Dependent Transcription
Cyclin T1, together with the kinase CDK9, is a component of the transcription elongation factor P-TEFb which binds the human immunodeficiency virus type 1 (HIV-1) transactivator Tat. P-TEFb facilitates transcription by phosphorylating the carboxy-terminal domain (CTD) of RNA polymerase II. Cyclin T1...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2003
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC151712/ https://ncbi.nlm.nih.gov/pubmed/12588988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.5.1688-1702.2003 |
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