The Growth Factor Granulin Interacts with Cyclin T1 and Modulates P-TEFb-Dependent Transcription

Cyclin T1, together with the kinase CDK9, is a component of the transcription elongation factor P-TEFb which binds the human immunodeficiency virus type 1 (HIV-1) transactivator Tat. P-TEFb facilitates transcription by phosphorylating the carboxy-terminal domain (CTD) of RNA polymerase II. Cyclin T1...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Hoque, Mainul, Young, Tara M., Lee, Chee-Gun, Serrero, Ginette, Mathews, Michael B., Pe'ery, Tsafi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2003
Assuntos:	Transcriptional Regulation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151712/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12588988/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.5.1688-1702.2003
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