Drug-Induced Reactivation of Apoptosis Abrogates HIV-1 Infection

HIV-1 blocks apoptosis, programmed cell death, an innate defense of cells against viral invasion. However, apoptosis can be selectively reactivated in HIV-infected cells by chemical agents that interfere with HIV-1 gene expression. We studied two globally used medicines, the topical antifungal ciclo...

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主要な著者: Hanauske-Abel, Hartmut M., Saxena, Deepti, Palumbo, Paul E., Hanauske, Axel-Rainer, Luchessi, Augusto D., Cambiaghi, Tavane D., Hoque, Mainul, Spino, Michael, Gandolfi, Darlene D'Alliessi, Heller, Debra S., Singh, Sukhwinder, Park, Myung Hee, Cracchiolo, Bernadette M., Tricta, Fernando, Connelly, John, Popowicz, Anthony M., Cone, Richard A., Holland, Bart, Pe’ery, Tsafi, Mathews, Michael B.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781084/
https://ncbi.nlm.nih.gov/pubmed/24086341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074414
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