Drug-Induced Reactivation of Apoptosis Abrogates HIV-1 Infection

HIV-1 blocks apoptosis, programmed cell death, an innate defense of cells against viral invasion. However, apoptosis can be selectively reactivated in HIV-infected cells by chemical agents that interfere with HIV-1 gene expression. We studied two globally used medicines, the topical antifungal ciclo...

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Autors principals: Hanauske-Abel, Hartmut M., Saxena, Deepti, Palumbo, Paul E., Hanauske, Axel-Rainer, Luchessi, Augusto D., Cambiaghi, Tavane D., Hoque, Mainul, Spino, Michael, Gandolfi, Darlene D'Alliessi, Heller, Debra S., Singh, Sukhwinder, Park, Myung Hee, Cracchiolo, Bernadette M., Tricta, Fernando, Connelly, John, Popowicz, Anthony M., Cone, Richard A., Holland, Bart, Pe’ery, Tsafi, Mathews, Michael B.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781084/
https://ncbi.nlm.nih.gov/pubmed/24086341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074414
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