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Low-Density Lipoprotein Receptor Related protein-1 (LRP1)-Dependent Cell Signaling Promotes Neurotrophic Activity in Embryonic Sensory Neurons

Developing sensory neurons require neurotrophic support for survival, neurite outgrowth and myelination. The low-density lipoprotein receptor-related protein-1 (LRP1) transactivates Trk receptors and thereby functions as a putative neurotrophin. Herein, we show that LRP1 is abundantly expressed in d...

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Detalhes bibliográficos
Main Authors: Yamauchi, Kazuyo, Yamauchi, Tomonori, Mantuano, Elisabetta, Murakami, Kenichi, Henry, Kenneth, Takahashi, Kazuhisa, Campana, Wendy Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781060/
https://ncbi.nlm.nih.gov/pubmed/24086544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075497
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