The Unfolded Protein Response Is a Major Mechanism by Which LRP1 Regulates Schwann Cell Survival after Injury

In peripheral nerve injury, Schwann cells (SCs) must survive to exert a continuing and essential role in successful nerve regeneration. Herein, we show that peripheral nerve injury is associated with activation of endoplasmic reticulum (ER) stress and the adaptive unfolded protein response (UPR). Th...

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Detalhes bibliográficos
Main Authors: Mantuano, Elisabetta, Henry, Kenneth, Yamauchi, Tomonori, Hiramatsu, Nobuhiko, Yamauchi, Kazuyo, Orita, Sumihisa, Takahashi, Kazuhisa, Lin, Jonathan H., Gonias, Steven L., Campana, W. Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188465/
https://ncbi.nlm.nih.gov/pubmed/21940431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2850-11.2011
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