The Unfolded Protein Response Is a Major Mechanism by Which LRP1 Regulates Schwann Cell Survival after Injury

In peripheral nerve injury, Schwann cells (SCs) must survive to exert a continuing and essential role in successful nerve regeneration. Herein, we show that peripheral nerve injury is associated with activation of endoplasmic reticulum (ER) stress and the adaptive unfolded protein response (UPR). Th...

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Hlavní autoři: Mantuano, Elisabetta, Henry, Kenneth, Yamauchi, Tomonori, Hiramatsu, Nobuhiko, Yamauchi, Kazuyo, Orita, Sumihisa, Takahashi, Kazuhisa, Lin, Jonathan H., Gonias, Steven L., Campana, W. Marie
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188465/
https://ncbi.nlm.nih.gov/pubmed/21940431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2850-11.2011
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