High Incidence of HPV-Associated Head and Neck Cancers in FA Deficient Mice Is Associated with E7’s Induction of DNA Damage through Its Inactivation of Pocket Proteins

Fanconi anemia (FA) patients are highly susceptible to solid tumors at multiple anatomical sites including head and neck region. A subset of head and neck cancers (HNCs) is associated with ‘high-risk’ HPVs, particularly HPV16. However, the correlation between HPV oncogenes and cancers in FA patients...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Park, Jung Wook, Shin, Myeong-Kyun, Pitot, Henry C., Lambert, Paul F.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781031/
https://ncbi.nlm.nih.gov/pubmed/24086435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075056
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