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Deficiencies in the Fanconi Anemia DNA damage Response Pathway Increase Sensitivity to HPV-Associated Head and Neck Cancer
Patients with the rare genetic disease, Fanconi Anemia (FA), are highly susceptible to squamous cell carcinomas arising at multiple anatomical sites including the head and neck region. Human papillomaviruses (HPVs), particularly HPV16, are associated with ~20% of head and neck squamous cell carcinom...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2999655/ https://ncbi.nlm.nih.gov/pubmed/20935219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1291 |
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