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Loss of Dependence on Continued Expression of the Human Papillomavirus 16 E7 Oncogene in Cervical Cancers and Precancerous Lesions Arising in Fanconi Anemia Pathway-Deficient Mice

Fanconi anemia (FA) is a rare genetic disorder caused by defects in DNA damage repair. FA patients often develop squamous cell carcinoma (SCC) at sites where high-risk human papillomaviruses (HPVs) are known to cause cancer, including the cervix. However, SCCs found in human FA patients are often HP...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Park, Soyeong, Park, Jung Wook, Pitot, Henry C., Lambert, Paul F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895109/
https://ncbi.nlm.nih.gov/pubmed/27190216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00628-16
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