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High Incidence of HPV-Associated Head and Neck Cancers in FA Deficient Mice Is Associated with E7’s Induction of DNA Damage through Its Inactivation of Pocket Proteins

Fanconi anemia (FA) patients are highly susceptible to solid tumors at multiple anatomical sites including head and neck region. A subset of head and neck cancers (HNCs) is associated with ‘high-risk’ HPVs, particularly HPV16. However, the correlation between HPV oncogenes and cancers in FA patients...

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Autori principali: Park, Jung Wook, Shin, Myeong-Kyun, Pitot, Henry C., Lambert, Paul F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781031/
https://ncbi.nlm.nih.gov/pubmed/24086435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075056
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