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Safety mechanism assisted by the repressor of tetracycline (SMART) vaccinia virus vectors for vaccines and therapeutics

Replication-competent viruses, such as Vaccinia virus (VACV), are powerful tools for the development of oncolytic viral therapies and elicit superior immune responses when used as vaccine and immunotherapeutic vectors. However, severe complications from uncontrolled viral replication can occur, part...

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Podrobná bibliografie
Hlavní autoři: Grigg, Patricia, Titong, Allison, Jones, Leslie A., Yilma, Tilahun D., Verardi, Paulo H.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780884/
https://ncbi.nlm.nih.gov/pubmed/23988330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1314483110
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