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IL-18 Expression Results in a Recombinant Vaccinia Virus That Is Highly Attenuated and Immunogenic

Interferon-γ (IFN-γ) is an attenuating factor for vaccinia virus (VACV), decreasing its virulence in vivo by more than a million fold. It is also a highly effective adjuvant when administered at the time of immunization with protein antigens. However, recombinant VACV (rVACV) vaccines expressing IFN...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Verardi, Paulo H., Legrand, Fatema A., Chan, Kenneth S., Peng, Yue, Jones, Leslie A., Yilma, Tilahun D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Mary Ann Liebert, Inc. 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942681/
https://ncbi.nlm.nih.gov/pubmed/24168450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2013.0052
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