Inhibition of pancreatic carcinoma by homo- and heterocombinations of antibodies against EGF-receptor and its kin HER2/ErbB-2

Due to intrinsic aggressiveness and lack of effective therapies, prognosis of pancreatic cancer remains dismal. Because the only molecular targeted drug approved for pancreatic ductal adenocarcinoma is a kinase inhibitor specific to the epidermal growth factor receptor (EGFR), and this receptor coll...

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Bibliografiske detaljer
Main Authors: Maron, Ruth, Schechter, Bilha, Mancini, Maicol, Mahlknecht, Georg, Yarden, Yosef, Sela, Michael
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780883/
https://ncbi.nlm.nih.gov/pubmed/24003140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313857110
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