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Aptamer to ErbB-2/HER2 enhances degradation of the target and inhibits tumorigenic growth
Aptamers, oligonucleotides able to avidly bind cellular targets, are emerging as promising therapeutic agents, analogous to monoclonal antibodies. We selected from a DNA library an aptamer specifically recognizing human epidermal growth factor receptor 2 (ErbB-2/HER2), a receptor tyrosine kinase, wh...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3657787/ https://ncbi.nlm.nih.gov/pubmed/23630281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1302594110 |
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