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Interferon-γ induces progressive nigrostriatal degeneration and basal ganglia calcification
We report that CNS directed expression of Interferon (IFN) -γ results in basal ganglia calcification, reminiscent of human idiopathic basal ganglia calcification (IBGC), and nigrostriatal degeneration. Our results show that IFN-γ mediates age-progressive nigrostriatal degeneration in the absence of...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3780582/ https://ncbi.nlm.nih.gov/pubmed/21572432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2829 |
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