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Chronic mild sleep restriction accentuates contextual memory impairments, and accumulations of cortical Aβ and pTau in a mouse model of Alzheimer’s Disease

Age-associated dysregulation of sleep can be worsened by Alzheimer’s disease (AD). AD and sleep restriction both impair cognition, yet it is unknown if mild chronic sleep restriction modifies the proteopathic processes involved in AD. The goal of this work was to test the hypothesis that sleep restr...

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書誌詳細
主要な著者: Rothman, Sarah M., Herdener, Nathan, Frankola, Kathryn A., Mughal, Mohamed R., Mattson, Mark P.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779872/
https://ncbi.nlm.nih.gov/pubmed/23856323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2013.07.010
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