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Substrate specificity and the effect of calcium on Trypanosoma brucei metacaspase 2

Metacaspases are cysteine peptidases found only in yeast, plants and lower eukaryotes, including the protozoa. To investigate the extended substrate specificity and effects of Ca(2+) on the activation of these enzymes, detailed kinetic, biochemical and structural analyses were carried out on metacas...

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Bibliographic Details
Main Authors: Machado, Maurício F.M., Marcondes, Marcelo F., Juliano, Maria A., McLuskey, Karen, Mottram, Jeremy C., Moss, Catherine X., Juliano, Luiz, Oliveira, Vitor
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779824/
https://ncbi.nlm.nih.gov/pubmed/23506317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12248
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