Histamine Induces ATP Release from Human Subcutaneous Fibroblasts, via Pannexin-1 Hemichannels, Leading to Ca(2+) Mobilization and Cell Proliferation

Changes in the regulation of connective tissue ATP-mediated mechano-transduction and remodeling may be an important link to the pathogenesis of chronic pain. It has been demonstrated that mast cell-derived histamine plays an important role in painful fibrotic diseases. Here we analyzed the involveme...

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Detalles Bibliográficos
Autores principales: Pinheiro, Ana Rita, Paramos-de-Carvalho, Diogo, Certal, Mariana, Costa, Maria Adelina, Costa, Cristina, Magalhães-Cardoso, Maria Teresa, Ferreirinha, Fátima, Sévigny, Jean, Correia-de-Sá, Paulo
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779754/
https://ncbi.nlm.nih.gov/pubmed/23918924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.460865
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