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Glycerol-3-phosphate Acyltransferase (GPAT)-1, but Not GPAT4, Incorporates Newly Synthesized Fatty Acids into Triacylglycerol and Diminishes Fatty Acid Oxidation

Four glycerol-3-phosphate acyltransferase (GPAT) isoforms, each encoded by a separate gene, catalyze the initial step in glycerolipid synthesis; in liver, the major isoforms are GPAT1 and GPAT4. To determine whether each of these hepatic isoforms performs a unique function in the metabolism of fatty...

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Autori principali: Wendel, Angela A., Cooper, Daniel E., Ilkayeva, Olga R., Muoio, Deborah M., Coleman, Rosalind A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779725/
https://ncbi.nlm.nih.gov/pubmed/23908354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.485219
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