IFN-γ inhibits liver progenitor cell proliferation in HBV-infected patients and in 3,5-diethoxycarbonyl-1,4-dihydrocollidine diet-fed mice

BACKGROUND & AIMS: Proliferation of liver progenitor cells (LPCs) is associated with inflammation and fibrosis in chronic liver diseases. However, how inflammation and fibrosis affect LPCs remains obscure. METHODS: We examined the role of interferon (IFN)-γ, an important pro-inflammatory and ant...

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Hauptverfasser: Weng, Hong-lei, Feng, De-chun, Radaeva, Svetlana, Kong, Xiao-ni, Wang, Lei, Liu, Yan, Li, Qi, Shen, Hong, Gao, Yun-peng, Müllenbach, Roman, Munker, Stefan, Huang, Tong, Chen, Jia-lin, Zimmer, Vincent, Lammert, Frank, Mertens, Peter R, Cai, Wei-min, Dooley, Steven, Gao, Bin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779479/
https://ncbi.nlm.nih.gov/pubmed/23747755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2013.05.041
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