Disparate Cellular Basis of Improved Liver Repair in β-Catenin-Overexpressing Mice After Long-Term Exposure to 3,5-Diethoxycarbonyl-1,4-Dihydrocollidine

Administration of a hepatotoxic diet containing 0.1% 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC) induces biliary damage followed by hepatocyte injury, which is repaired through atypical ductular proliferation and oval cells and their subsequent differentiation to bile duct cells and hepatocytes....

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Detalhes bibliográficos
Main Authors: Thompson, Michael D., Awuah, Prince, Singh, Sucha, Monga, Satdarshan P.S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947277/
https://ncbi.nlm.nih.gov/pubmed/20813968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100173
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