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A TSPO ligand is protective in a mouse model of multiple sclerosis
Local production of neurosteroids such as progesterone and allopregnanolone confers neuroprotection in central nervous system (CNS) inflammatory diseases. The mitochondrial translocator protein (TSPO) performs a rate-limiting step in the conversion of cholesterol to pregnenolone and its steroid deri...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
WILEY-VCH Verlag
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3779450/ https://ncbi.nlm.nih.gov/pubmed/23681668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201202124 |
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