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PARP-1 Deficiency Increases the Severity of Disease in a Mouse Model of Multiple Sclerosis
Poly(ADP-ribose) polymerase-1 (PARP-1) has been implicated in the pathogenesis of several central nervous system (CNS) disorders. However, the role of PARP-1 in autoimmune CNS injury remains poorly understood. Therefore, we studied experimental autoimmune encephalomyelitis (EAE), a model for multipl...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2758007/ https://ncbi.nlm.nih.gov/pubmed/19628872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.013474 |
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