Bub3 reads phosphorylated MELT repeats to promote spindle assembly checkpoint signaling

Regulation of macromolecular interactions by phosphorylation is crucial in signaling networks. In the spindle assembly checkpoint (SAC), which enables errorless chromosome segregation, phosphorylation promotes recruitment of SAC proteins to tensionless kinetochores. The SAC kinase Mps1 phosphorylate...

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Main Authors: Primorac, Ivana, Weir, John R, Chiroli, Elena, Gross, Fridolin, Hoffmann, Ingrid, van Gerwen, Suzan, Ciliberto, Andrea, Musacchio, Andrea
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2013
Teme:
Biophysics and Structural Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779320/
https://ncbi.nlm.nih.gov/pubmed/24066227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01030
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