Intra- and inter-molecular effects of a conserved arginine residue of neuronal and inducible nitric oxide synthases on FMN and calmodulin binding

Nitric oxide synthases (NOSs) synthesize nitric oxide (NO), a signaling molecule, from l-arginine, utilizing electrons from NADPH. NOSs are flavo-hemo proteins, with two flavin molecules (FAD and FMN) and one heme per monomer, which require the binding of calcium/calmodulin (Ca(2+)/CaM) to produce N...

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Bibliographische Detailangaben
Hauptverfasser: Panda, Satya Prakash, Polusani, Srikanth R., Kellogg, Dean L., Venkatakrishnan, Priya, Roman, Madeline G., Demeler, Borries, Masters, Bettie Sue S., Roman, Linda J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779284/
https://ncbi.nlm.nih.gov/pubmed/23507581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2013.03.004
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