Conditional Deletion of Cytochrome P450 Reductase in Osteoprogenitor Cells Affects Long Bone and Skull Development in Mice Recapitulating Antley-Bixler Syndrome: Role of a Redox Enzyme in Development

NADPH-cytochrome P450 oxidoreductase (POR) is the primary electron donor for cytochromes P450, dehydrocholesterol reductase, heme oxygenase, and squalene monooxygenase. Human patients with specific mutations in POR exhibit severe developmental malformations including disordered steroidogenesis, sexu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Panda, Satya P., Guntur, Anyonya R., Polusani, Srikanth R., Fajardo, Roberto J., Gakunga, Peter T., Roman, Linda J., Masters, Bettie Sue
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783497/
https://ncbi.nlm.nih.gov/pubmed/24086598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075638
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados