Doublecortin Knockout Mice Show Normal Hippocampal-Dependent Memory Despite CA3 Lamination Defects

Mutations in the human X-linked doublecortin gene (DCX) cause major neocortical disorganization associated with severe intellectual disability and intractable epilepsy. Although Dcx knockout (KO) mice exhibit normal isocortical development and architecture, they show lamination defects of the hippoc...

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Main Authors: Germain, Johanne, Bruel-Jungerman, Elodie, Grannec, Gael, Denis, Cécile, Lepousez, Gabriel, Giros, Bruno, Francis, Fiona, Nosten-Bertrand, Marika
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779246/
https://ncbi.nlm.nih.gov/pubmed/24073232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074992
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