Doublecortin Knockout Mice Show Normal Hippocampal-Dependent Memory Despite CA3 Lamination Defects

Mutations in the human X-linked doublecortin gene (DCX) cause major neocortical disorganization associated with severe intellectual disability and intractable epilepsy. Although Dcx knockout (KO) mice exhibit normal isocortical development and architecture, they show lamination defects of the hippoc...

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Autors principals: Germain, Johanne, Bruel-Jungerman, Elodie, Grannec, Gael, Denis, Cécile, Lepousez, Gabriel, Giros, Bruno, Francis, Fiona, Nosten-Bertrand, Marika
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779246/
https://ncbi.nlm.nih.gov/pubmed/24073232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074992
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